Enamine ltd.

23 Alexandra Matrosova Street
01103 KIEV
Ukraine

Phone: 0038 044 537 32 18
Fax: 0038 044 537 32 53
E-Mail: enamine@enamine.netThis e-mail address is being protected from spam bots, you need JavaScript enabled to view it
Stock symbol: targeted l

Description:

ENAMINE – Smart Chemistry Solutions
SCREENING COMPOUNDS, BUILDING BLOCKS, CUSTOM SYNTHESIS, DISCOVERY CHEMISTRY AND CONTRACT RESEARCH FOR DRUG DISCOVERY
Screening compounds are in the main focus of Enamine production activity. Key products of Enamine also include building blocks, targeted libraries and focused libraries. We provide fully integrated smart chemistry solutions for drug design and development: custom synthesis, contract research, lead generation and optimization programs.

SCREENING COMPOUNDS
Screening collection of Enamine consists of more than 900,000 low molecular weight organic compounds. It proved to be a valuable source of exclusive drug-like compounds. They have been produced by application of original synthetic techniques developed by Enamine. We offer prompt resupply and resynthesis of compounds from our collection.

By application of drug-like and structural filters (Lipinski’s and Veber’s rules, MedChem filters) to our Screening Collection we have developed a Drug-Like library of 600,000 compounds.

Enamine supplies only products of the highest quality. Enamine carries out total Quality Control by LC/MS and NMR at proprietary facilities.

SCREENING COMPOUNDS FROM REAL DATABASE
REAL DataBase is the pool of chemical structures reflecting major part of chemical space immediately accessible to Enamine via use-proven reactions involving building blocks available from stock. This chemical space is validated by excessive testing of our original procedures under standardized conditions to ensure reliability of results. Currently, 10,000,000 highly feasible structures are offered for synthesis at a very competitive prices. Compounds can be ready for dispatch within 6-8 weeks.

BUILDING BLOCKS
Building blocks design is based on the expertise of Enamine team and its scientific partners in heterocyclic, fluorine, sulfur and other chemistries. Enamine has elaborated a large stock of proprietary building blocks (18,000 items). Purity of over 95% is standard, spectral data and certificates of analysis along with MSDS are available upon request. Utilisation of building blocks as stating materials in the in-house production has resulted in high percentage of unique derivatives of these compounds in our Screening Collection.

CUSTOM SYNTHESIS
Custom synthesis belongs to one of the prioritized directions of Enamine development. Our well-equipped laboratories, highly qualified personnel and vast scientific background enable us to challenge different custom synthesis tasks in mg/g/kg scale.

Custom Synthesis programs can be developed either on ‘project-by-project’ or FTE basis.

DISCOVERY CHEMISTRY
Discovery chemistry opportunities provided by Enamine attract a growing attention of pharmaceutical companies worldwide. It is not only because Enamine FTE rate is one of the most competitive in the Eastern Europe, but also because of introduction of a number of enabling technologies, first of all the state-of-the-art ChemoInformatics.

CHEMINFORMATICS AND MOLECULAR MODELING
Computational chemistry provides an increasing input to Enamine products and services. Molecular modeling department is developing targeted libraries against four most important enzyme classes: proteases, kinesis, GPCR and ion channels. Carefully selected by in silico screening and validated by in vitro assays Enamine targeted libraries provide an excellent cost-effective solution for drug development.

GET ADDITIONAL INFORMATION
Visit our web-site www.enamine.net to find out more about Enamine services and products. Customers can browse database of screening compounds and building blocks on-line, search for compounds and instantly place orders. Registered users also can download current databases for off-line use.

FDIchemical

Vishnyakivskaya 7b, off.267
02140
Ukraine

Phone: +380503012696
Fax: +380503012696

Description:

FDIchemical LTD is involved in development and synthesis of new organic molecules and scale-up synthesis. We produce an ample quantity of screening compounds and building blocks. Our available collection of diverse structures contains very promising compounds which can be the matter of your interest. Presently we have about 10,0000 screening compounds and over 1000 building blocks. Quality all of the compounds is 90%+ and it was checked with NMR and/or HPLC. We warrant prompt packing of the compounds in vials or plates in different amounts and delivery.